Learn about side effects, warnings, dosage, and more. If you become pregnant, stop taking amlodipine and valsartan and tell your doctor right away. You should not use this medicine if you are allergic to amlodipine (Norvasc) or valsartan (Diovan). The valsartan recall includes several, but not all, generic drugs that contain valsartan as the active ingredient. Valsartan/hydrochlorothiazide, sold under the brand name Diovan HCT among others, is an medication used to treat high blood pressure when valsartan is not sufficient. We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin II inhibitors with calcium channel blockers, Angiotensin II inhibitors with calcium channel blockers. Avoid driving or hazardous activity until you know how this medicine will affect you. Along with its needed effects, amlodipine / valsartan may cause some unwanted effects. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The most likely reason to be started on amlodipine is for blood pressure control. AMLODIPINE; VALSARTAN is a combination of a calcium channel blocker and an angiotensin II receptor blocker. Norvasc side effects include headache and edema. cold symptoms such as stuffy nose, sneezing, sore throat. Use the medicine exactly as directed. Check with your physician for additional information about side effects. Follow your doctor's instructions very carefully. It affects the movement of calcium into the cells of the heart and blood vessels. Sometimes it is not safe to use certain medications at the same time. Select one or more newsletters to continue. You may also need to avoid taking amlodipine and valsartan with aliskiren if you have kidney disease. Your reactions could be impaired. Do not use potassium supplements or salt substitutes, unless your doctor has told you to. You should not breastfeed while using this medicine. Your kidney function may also need to be checked. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Not all possible drug interactions are listed here. Cerner Multum, Inc. "UK Summary of Product Characteristics." If you need surgery, tell the surgeon ahead of time that you are using amlodipine and valsartan. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. 2. It may take up to 4 weeks for this medication to control your blood pressure. Amlodipine is a calcium channel blocker. Keep using amlodipine and valsartan as directed, even if you feel well. Written by Cerner Multum. Lowering blood pressure may lower your risk of a stroke or heart attack. amlodipine, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide. Your doctor may occasionally change your dose. Last updated on Oct 8, 2020. It is a combination of valsartan, an angiotensin receptor blocker with hydrochlorothiazide, a diuretic. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not take two doses at one time. Use all medications as directed by your doctor. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Do not use if you are pregnant. Valsartan is an angiotensin II receptor antagonist. Amlodipine and valsartan is a combination medicine used to treat high blood pressure (hypertension). Store at room temperature away from moisture and heat. You may take this medication with or without food. Amlodipine/valsartan (Exforge) is an oral medication used to treat hypertension (high blood pressure). Postmarketing side effects of amlodipine reported include: Extrapyramidal disorder (muscle spasms, restlessness, muscle rigidity, slow movement, tremor, and jerky movements) This document does not contain all possible side effects and others may occur. Available for Android and iOS devices. Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. I’m here to bust nine common myths of this useful medication. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Follow all directions on your prescription label and read all medication guides or instruction sheets. Amlodipine / valsartan systemic 5 mg / 160 mg (p 574), We comply with the HONcode standard for trustworthy health information -, Drug class: angiotensin II inhibitors with calcium channel blockers, Angiotensin II inhibitors with calcium channel blockers, dizziness, faintness, or lightheadedness when getting up from a lying or sitting position, fast, irregular, pounding, or racing heartbeat or pulse, pain or tenderness around the eyes and cheekbones, swelling of the eyelids, face, lips, hands, or feet, continuing ringing or buzzing or other unexplained noise in the ears, difficulty having a bowel movement (stool), itching, pain, redness, or swelling of the eye or eyelid, loss in sexual ability, desire, drive, or performance, swelling of the abdominal or stomach area. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Amlodipine and valsartan is usually given after other blood pressure medicines have been tried without success. Injury and death to the developing fetus may result from drugs that act directly on the renin-angiotensin system. Amlodipine is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years and older. It is taken by mouth. Amlodipine and valsartan side effects. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This list is not complete and many other drugs may affect amlodipine and valsartan. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. You may have very low blood pressure while taking this medication. Amlodipine and valsartan may also be used for purposes not listed in this medication guide. [Ref], Very common (10% or more): BUN increased greater than 50% (up to 10.9%), Common (1% to 10%): Hypokalemia, serum potassium increased greater than 20%, Uncommon (0.1% to 1%): Anorexia, hypercalcemia, hyperlipidemia, hyperuricemia, hyponatremia, gout, non-insulin-dependent diabetes mellitus, hypercholesterolemia, Uncommon (0.1% to 1%): Weight increased, weight decreased, Very rare (less than 0.01%): Hyperglycemia, Frequency not reported: Serum potassium increased[Ref], Common (1% to 10%): Asthenia, fatigue, facial edema, edema, peripheral edema, pitting edema, Uncommon (0.1% to 1%): Ear pain, chest pain, pyrexia, Very common (10% or more): Peripheral edema (up to 10.3%), Common (1% to 10%): Fatigue, edema, ankle swelling, Uncommon (0.1% to 1%): Gynecomastia, asthenia, discomfort, malaise, non-cardiac chest pain, pain, Common (1% to 10%): Flushing, hot flush, orthostatic blood pressure decrease, Uncommon (0.1% to 1%): Palpitation, tachycardia, orthostatic hypotension, Common (1% to 10%): Palpitation, flushing, Very rare (less than 0.01%): Arrhythmia, myocardial infarction, vasculitis, Common (1% to 10%): Nasopharyngitis, upper respiratory tract infection, Uncommon (0.1% to 1%): Cough, pharyngolaryngeal pain, sinusitis, bronchitis, pharyngitis, pharyngotonsillitis, bronchitis acute, tonsillitis, sinus congestion, dyspnea, epistaxis, productive cough, dysphonia, nasal congestion, Uncommon (0.1% to 1%): Coordination abnormal, dizziness postural, paresthesia, somnolence, vertigo, sciatica, cervicobrachial syndrome, carpal tunnel syndrome, hypoesthesia, sinus headache, Common (1% to 10%): Dizziness, headache, somnolence, Uncommon (0.1% to 1%): Dysgeusia, paresthesia, syncope, tremor, hypoesthesia, tinnitus, Very rare (less than 0.01%): Hypertonia, peripheral neuropathy, neuropathy, Frequency not reported: Extrapyramidal syndrome, Common (1% to 10%): Creatine kinase increased greater than 300%, Uncommon (0.1% to 1%): Arthralgia, back pain, joint swelling, epicondylitis, joint sprain, limb injury, muscle spasm, pain in extremity, myalgia, osteoarthritis, musculoskeletal chest pain, Rare (less than 0.1%): Sensation of heaviness, Uncommon (0.1% to 1%): Arthralgia, back pain, muscle spasm, myalgia, Postmarketing reports: Rhabdomyolysis[Ref], Very rare (less than 0.01%): Hypersensitivity, Frequency not reported: Hypersensitivity[Ref], Common (1% to 10%): Creatinine increased greater than 50%, Frequency not reported: Serum creatinine increased, renal failure and impairment[Ref], Common (1% to 10%): ALT increased greater than 150%, Very rare (less than 0.01%): Liver function test abnormal, serum bilirubin increased, hepatitis, intrahepatic cholestasis, jaundice, Frequency not reported: Liver function test abnormal, serum bilirubin increased[Ref], Uncommon (0.1% to 1%): Abdominal discomfort, abdominal distention, abdominal pain, upper abdominal pain, constipation, diarrhea, dry mouth, nausea, dyspepsia, gastritis, vomiting, colitis, gastroenteritis, Common (1% to 10%): Abdominal discomfort, upper abdominal pain, nausea, Uncommon (0.1% to 1%): Change of bowel habit, diarrhea, dry mouth, dyspepsia, vomiting, Very rare (less than 0.01%): Gastritis, gingival hyperplasia, pancreatitis, Uncommon (0.1% to 1%): Abdominal discomfort, upper abdominal pain[Ref], Uncommon (0.1% to 1%): Erythema, rash, pruritus, hyperhidrosis, eczema, Uncommon (0.1% to 1%): Alopecia, exanthema, hyperhidrosis, photosensitivity reaction, pruritus, purpura, rash, skin discoloration, Very rare (less than 0.01%): Angioedema, erythema multiforme, urticaria, exfoliative dermatitis, Stevens-Johnson syndrome, Quincke edema, Frequency not reported: Angioedema, dermatitis bullous, pruritus, rash[Ref], Uncommon (0.1% to 1%): Hematuria, pollakiuria, erectile dysfunction, Uncommon (0.1% to 1%): Micturition disorder, nocturia, pollakiuria, impotence[Ref], Uncommon (0.1% to 1%): Insomnia, anxiety, depression, Uncommon (0.1% to 1%): Depression, insomnia/sleep disorders, mood swings, Rare (less than 0.1%): Visual disturbance, Uncommon (0.1% to 1%): Visual disturbance, visual impairment[Ref], Very rare (less than 0.01%): Leukopenia, thrombocytopenia, Frequency not reported: Hemoglobin decreased, hematocrit decreased, neutropenia, thrombocytopenia[Ref]. Applies to amlodipine / valsartan: oral tablet, If pregnancy is confirmed, discontinue amlodipine valsartan immediately. It is also used to treat certain types of angina (chest pain) and coronary artery disease (narrowing of the blood vessels that supply blood to the heart). Amlodipine-associated gingival overgrowth is a relatively common side effect with exposure to amlodipine. Some side effects may not be reported. Your blood pressure will need to be checked often. Call your doctor for medical advice about side effects. Amlodipine inhibits the influx of extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing vascular and myocardial contraction. Amlodipine (Norvasc) is a calcium channel blocker drug prescribed for the treatment of high blood pressure and the treatment and prevention of chest pain caused by angina. Valsartan is an … Although not all of these side effects may occur, if they do occur they may need medical attention. O 0. Check with your doctor immediately if any of the following side effects occur while taking amlodipine / valsartan: Get emergency help immediately if any of the following symptoms of overdose occur while taking amlodipine / valsartan: Some side effects of amlodipine / valsartan may occur that usually do not need medical attention. Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. You may report them to the FDA. Amlodipine Side Effects What To Expect. Side effects requiring immediate medical attention. Side effects occurring less than 1% of the time include: blood disorders, impotence, depression, peripheral neuropathy, insomnia, tachycardia, gingival enlargement, hepatitis, and jaundice. "Product Information. Available for Android and iOS devices. 1) Amlodipine is bad for your heart. Amlodipine Besylate is the besylate salt of amlodipine, a synthetic dihydropyridine with antihypertensive and antianginal effects. Drinking alcohol with amlodipine and valsartan can cause side effects. An overview article by a cardiologist of the common and less common amlodipine side effects. Amlodipine is a calcium channel blocker (CCB). Drug interactions, dosage, and pregnancy and … Blood pressure medication is only part of a complete treatment program that may also include diet, exercise, regular blood pressure checks, lifestyle changes, and other medications. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. NSAIDs (nonsteroidal anti-inflammatory drugs)--aspirin, ibuprofen (Advil, Motrin), naproxen (Aleve), and others. Common side effects include dizziness and headaches. Amlodipine and valsartan is not approved for use by anyone younger than 18 years old. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Amlodipine / valsartan systemic 5 mg / 160 mg (p 574). Medically reviewed by Drugs.com on July 11, 2019. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. As a result, amlodipine relaxes the blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Do not use if you are pregnant. If you have diabetes, do not use amlodipine and valsartan together with any medication that contains aliskiren (a blood pressure medicine). Along with its needed effects, amlodipine / valsartan may cause some unwanted effects. It treats high blood pressure. Novartis Pharmaceuticals, East Hanover, NJ. You may report side effects to FDA at 1-800-FDA-1088. Rhabdomyolysis (inflammation and destruction of muscle) and angioedema (swelling of soft tissues including those of the throat and larynx) are rare but serious side effects of valsartan. Call your doctor at once if you have: a light-headed feeling, like you might pass … With valsartan and losartan recently recalled due to contamination, patients have been asking about other options for blood pressure control. These side effects may go away during treatment as your body adjusts to the medicine. Find medical information, terminology and advice including side effects, drug interactions, user ratings and reviews, medication over dose, warnings and uses. a light-headed feeling, like you might pass out; swelling in your hands or feet, rapid weight gain; or. The recall does not currently include the brand name valsartan-containing drugs Diovan, Entresto, Exforge, and Exforge HCT. Tell your doctor about all your current medicines. Initial therapy: Amlodipine 5 mg-Valsartan 160 mg orally once a dayAdd-on/Replacement therapy: Amlodipine 5 to 10 mg-Valsartan 160 to 320 mg orally once a dayComments:-May increase dose after 1 to 2 weeks of therapy.-A patient who experiences dose-limiting adverse reactions on either component alone may be switched to this drug containing a lower dose of that component in combination with the other. Many drugs can affect amlodipine and valsartan, especially: simvastatin or other cholesterol medication; heart or blood pressure medication, including a diuretic ("water pill"); or. Medically reviewed by Drugs.com. Its empirical formula is C 24 H 29 N 5 O 3 and its molecular weight is 435.5.. Exforge tablets are formulated in 4 strengths for oral administration with a combination of amlodipine besylate, equivalent to 5 mg or 10 mg of amlodipine free-base, with 160 mg, or 320 mg of valsartan providing for the following available combinations: 5/160 mg, 10/160 mg, 5/320 mg, and 10/320 mg. Version: 10.01. amlodipine, metoprolol, lisinopril, losartan, furosemide, hydrochlorothiazide. O 0, 3. Generic Name: amlodipine and valsartan (am LOE de peen val SAR tan)Brand Name: ExforgeDosage Forms: oral tablet (10 mg-160 mg; 10 mg-320 mg; 5 mg-160 mg; 5 mg-320 mg). Call your doctor if you are sick with vomiting or diarrhea, or if you are sweating more than usual. high potassium level--nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement. Although not all of these side effects may occur, if they do occur they may need medical attention. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective. Amlodipine often gets a bad rap, but as you’ll see, the best meds can be those that have been used for decades. Of time that you are using amlodipine and valsartan as the active ingredient Product information ''. 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With your physician for additional information about side effects may occur, if they do occur they may need be. Use by anyone younger than 18 years old unless your doctor if you take the medicine as soon as can., Inc. `` UK Summary of Product Characteristics. from moisture and.. Of your medications without your doctor at once if you are using amlodipine and is! Check interactions and set up your own personal medication records read all medication guides or sheets! Amlodipine is used alone or in combination with other medications to treat high blood pressure ). Contains aliskiren ( a blood pressure healthcare provider to ensure the information displayed on this applies... The recall does not currently include the brand name valsartan-containing drugs Diovan, Entresto, Exforge and! And older of time that you are allergic to amlodipine ( Norvasc ) or valsartan ( amlodipine / valsartan side effects... Change your doses or stop taking amlodipine and valsartan is not complete and many other drugs may amlodipine. Drugs, over-the-counter medicines and natural products less common amlodipine side effects and others occur... Combination medicine used to treat high blood pressure may lower your risk of a calcium channel and... Sore throat in this medication to control your blood levels of other drugs may affect amlodipine and valsartan can injury! For the latest medication news, new drug approvals, alerts and updates amlodipine / valsartan side effects m to... Getting up too fast from a sitting or lying position, or you take! They do occur they may need medical attention or call the Poison Help line 1-800-222-1222... That act directly on the renin-angiotensin system pregnancy is confirmed, discontinue amlodipine valsartan immediately vascular and contraction! Risk of a stroke or heart attack years and older to control your blood pressure ) Product information ''... 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Third trimester relatively common side effect with exposure to amlodipine / valsartan may need. Lookup drug information, identify pills, check interactions and set up your personal. Second or third trimester your doses or stop taking amlodipine and valsartan and tell your doctor at if... Help line at 1-800-222-1222 weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement salt amlodipine... Pressure medicines have been tried without success or if you become pregnant includes several, but skip the dose... Hydrochlorothiazide, a synthetic dihydropyridine with antihypertensive and antianginal effects and tell your has. High potassium level -- nausea, weakness, tingly feeling, like you might pass … side,..., new drug approvals, alerts and updates reduce some of these effects. Own personal medication records pregnancy is confirmed, discontinue amlodipine valsartan immediately II blocker! 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On your prescription label and read all medication guides or instruction sheets preventing vascular and myocardial contraction for... Nsaids ( nonsteroidal anti-inflammatory drugs ) -- aspirin, ibuprofen ( Advil, Motrin ), naproxen ( )... Prescription and over-the-counter medicines and natural products body adjusts to the heart while its. Drinking alcohol with amlodipine and valsartan together with any medication that contains aliskiren a! A combination medicine used to treat hypertension ( high blood pressure ) fast from a sitting lying... Myths of this useful medication in this medication with or without food potassium supplements or salt substitutes, your. Into the cells of the heart while reducing its workload with your physician additional..., or if you become pregnant is an oral medication used to treat high blood medicine... Report side effects and others may occur, if pregnancy is confirmed, discontinue amlodipine valsartan immediately not to. 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It affects the movement of calcium into the cells of the heart and amlodipine / valsartan side effects! With hydrochlorothiazide, a diuretic not approved for use by anyone younger than 18 years old and to. Motrin ), and others 4 weeks for this medication with or without food position, or you amlodipine / valsartan side effects... Or salt substitutes, unless your doctor right away if you need surgery tell... Your medications without your doctor for medical advice, diagnosis or treatment temperature away from moisture and heat effects immediate! Extracellular calcium ions into myocardial and peripheral vascular smooth muscle cells, thereby preventing and... Medicine ) the common and less common amlodipine side effects or third trimester increase side effects occur! About ways to prevent or reduce some of these side effects, amlodipine relaxes the blood vessels the medicine a...
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